News

Wilke Cohen Lyme Disease Project Update & Site Visit

It has been a year of milestones for the Wilke Cohen Lyme Disease Project. ISB received a transformational, multi-year pledge of $3 million from the Steven & Alexandra Cohen Foundation (read press release) and another magnanimous gift from Jeff and Liesl Wilke, who spearheaded the launch of the project in 2015. Our research team was also thrilled to be able to host Jeff and Liesl Wilke and Alex Cohen for…

NIH Research Matters features ISB’s MTB paper

NIH Research Matters published an article on our tuberculosis paper. “The incredibly large number of possible drug combinations taken together with the difficulty of growing Mtb in the laboratory make discovery of effective combination therapy extremely challenging,” Dr. Nitin Baliga says. “We hope that our systems-based strategy will accelerate TB drug discovery by helping researchers prioritize combinations that are more likely to be effective.” READ THE ARTICLE

Wilke Cohen Lyme Disease Project Receives $3M from the Steven & Alexandra Cohen Foundation

PRESS RELEASE Total Funding Has Reached $6.1 Million ISB Researchers Have Discovered Potential Biomarkers and Successfully Reproduced the Borrelia Bacteria in the Lab SEATTLE – June 1, 2016 – Institute for Systems Biology (ISB) has received a transformational, multi-year pledge from the Steven & Alexandra Cohen Foundation to support the Wilke Cohen Lyme Disease Project. In addition to an initial $3.1 million in funding from Jeff and Liesl Wilke, Jeff…

Learning from microalgae as ‘biofactories’

In a newly published research, former members of the Price lab Saheed Imam and Sascha Schäuble, in collaboration with the Baliga lab, share discoveries from their studies of Chlamydomonas reinhardtii – Chlamy for short. What follows is a short excerpt: To the casual observer, algae may appear to be a nuisance. But for researchers, photosynthetic microalgae and other microbes have the potential to become sustainable biofactories that can economically produce renewable…

ISB launches 3-Year Wilke Lyme Disease project

Study Utilizes Systems Approaches to Develop Diagnostics and Deeper Understanding of Chronic Lyme The Institute for Systems Biology (ISB) has received $2.13 million in transformational gifts from Jeff and Liesl Wilke; Jeff and MacKenzie Bezos; and the Bay Area Lyme Foundation to tackle chronic Lyme disease, a highly complex and often misdiagnosed disease that can be debilitating for those who do not respond to a standard course of antibiotics. This funding…

NIH-led effort – including ISB – launches Big Data portal for Alzheimer’s drug discovery

The National Institutes of Health announced the launch of a new Alzheimer’s Big Data portal, which includes the first wave of data for use by the research community. This portal is the result of the Accelerating Medicines Partnership (AMP) program, which focuses on facilitating collaboration among government agencies, academia and industry in order to translate research more quickly to therapies. The launch of the AMP Alzeheimers Disease Knowledge Portal is…

A ‘Google map’ of Human Metabolism

Nathan Price and Vangelis Simeonidis, a visiting scholar from Luxembourg Centre for Systems Biomedicine (LCSB is a major strategic partner with ISB), contributed to this paper – “A community-driven global reconstruction of human metabolism” – that was published today in Nature Biotechnology. An excerpt describing the collaborative project from a press release is below. An interactive map is forthcoming.   From Medicalxpress.com: “An international consortium of university researchers has produced…