Institute for Systems Biology and Arivale “Pioneer 100 Study” Establishes Foundation for New Industry of Scientific Wellness. Personal, dense, dynamic data clouds enable novel insights into mechanisms of wellness and disease, new approaches to biomarker discovery, and the empowerment of individuals to enhance their own health.
Seattle’s Magnificent Forest at Seward Park is located within one of the nation’s most diverse neighborhoods. The 98118 zip code in southeast Seattle is home to people of all socioeconomic classes including groups of immigrants who speak more than 60 languages. Seward Park serves as an urban oasis for the community to enjoy nature, easy hikes, and access to the expansive Lake Washington. The park’s Magnificent Forest, so called because…
Congratulations to Alison Paquette who recently was promoted to Research Scientist in the Price Lab. Alison received her PhD in Experimental and Molecular Medicine at the Geisel School of Medicine at Dartmouth. She is interested in identifying molecular biomarkers that may predict preterm birth and adverse neonatal outcomes such as preeclampsia. “Pregnancy complications are not very well understood, and we are amongst the only labs really taking a systems biology…
April 25, 2017 A Cell-Surface Membrane Protein Signature for Glioblastoma 3 bullets: Using integrated protein and gene expression data, ISB researchers developed a 33-gene signature for glioblastoma, an aggressive form of brain cancer. Glioblastoma gene signatures are associated with TGF-b signaling and cancer invasion. Researchers think that some of the glioblastoma gene signatures have the potential to be used as blood biomarkers for this aggressive cancer. Read the full summary…
The Institute for Systems Biology has named James Heath, PhD, as its new president, effective January 2018. Heath is widely recognized as one of the world’s most accomplished scientists, working on fundamental problems at the interface of the chemical, physical, biological, and biomedical sciences, with focus areas of molecular biotechnologies and oncology. ISB’s co-founder and president Lee Hood, MD, PhD, was appointed senior vice president and chief science officer at…
Feb. 27, 2017 ISB researchers and colleagues from several institutes published a new study today in Human Molecular Genetics. The key points of the study “High resolution time-course mapping of early transcriptomic, molecular and cellular phenotypes in Huntington’s disease CAG knock-in mice across multiple genetic backgrounds” are: A multi-institute collaboration mapped in high resolution the earliest effects of the Huntington’s disease mutation in mice. The study included four different genetic…
‘Hyper Wellbeing’ is a summit to foster an emerging consumer technology industry. Consumer data-driven health, wellness and lifestyle optimization plus disease risk reduction. It represents a power shift towards the consumer and the future of mobile, wearables, health and wellness. Nathan Price presented at the Wellness as a Service World Summit, which took place on 14th November 2016 at the Computer History Museum (1401 N. Shoreline Blvd. Mountain View, CA…
It has been a year of milestones for the Wilke Cohen Lyme Disease Project. ISB received a transformational, multi-year pledge of $3 million from the Steven & Alexandra Cohen Foundation (read press release) and another magnanimous gift from Jeff and Liesl Wilke, who spearheaded the launch of the project in 2015. Our research team was also thrilled to be able to host Jeff and Liesl Wilke and Alex Cohen for…
Dr. Lee Hood, ISB president, and Nathan Price, ISB associate director, have joined the scientific advisory board of the newly launched Habit, which will begin to offer personalized nutrition plans based on your biology. From a recent Fast Company article: Neil Grimmer’s new startup, called Habit, aims to help others achieve their goals, whether it’s to lose weight or sleep more soundly. The company, which is launching in January, offers…
Nathan Price gave a talk titled “Genomics, Big Data, Informatics and the Future of Medicine” at the Personalized Lifestyle Medicine Institute‘s (PLMI) 2015 Thought Leaders Consortium (TLC), held in Chicago, October 24-25. The theme of the 2015 TLC was the Future of Genomics in Healthcare: from Personalized Cancer Therapy to Wellness.
NIH Research Matters published an article on our tuberculosis paper. “The incredibly large number of possible drug combinations taken together with the difficulty of growing Mtb in the laboratory make discovery of effective combination therapy extremely challenging,” Dr. Nitin Baliga says. “We hope that our systems-based strategy will accelerate TB drug discovery by helping researchers prioritize combinations that are more likely to be effective.” READ THE ARTICLE
PRESS RELEASE Total Funding Has Reached $6.1 Million ISB Researchers Have Discovered Potential Biomarkers and Successfully Reproduced the Borrelia Bacteria in the Lab SEATTLE – June 1, 2016 – Institute for Systems Biology (ISB) has received a transformational, multi-year pledge from the Steven & Alexandra Cohen Foundation to support the Wilke Cohen Lyme Disease Project. In addition to an initial $3.1 million in funding from Jeff and Liesl Wilke, Jeff…
Congratulations to our colleague Dani Bergey in the Price Lab for receiving a Huntington’s Disease Society of America (HDSA) Donald A. King Summer Research Fellowship. “This is going to be a great step for her as she prepares to apply for graduate school next year,” said Nathan Price.
ISB is participating in The Seattle Foundation’s sixth annual GiveBIG day on May 3! And, this year, you can schedule your gift in advance. GiveBIG is an annual, community-wide day of giving hosted by The Seattle Foundation that aims to inspire regional philanthropy. Between midnight and midnight (PST) on May 3rd, The Seattle Foundation and its generous sponsors will match a percentage of all contributions to local nonprofits. GiveBIG 2015 raised…
Dr. Leroy Hood to serve as chief science officer for Providence FOR IMMEDIATE RELEASE SEATTLE – March 14, 2016 – With the goal of bringing personalized medicine to every patient, Providence Health & Services and the Institute for Systems Biology announced today an affiliation that will transform health care to a proactive mode that is focused on keeping patients well and identifying the earliest opportunities to reverse or even prevent…
A 100k Wellness Project: A Data-Rich Longitudinal Study for the Digital Age was presented by Nathan Price, PhD at the Seattle Science Foundation‘s semi-monthly Spine Conference. Seattle Science Foundation is a non-profit organization dedicated to the international collaboration among physicians, scientists, technologists, engineers and educators. The Foundation’s training facilities and extensive internet connectivity have been designed to foster improvements in health care through professional medical education, training, creative dialogue and…
In a newly published research, former members of the Price lab Saheed Imam and Sascha Schäuble, in collaboration with the Baliga lab, share discoveries from their studies of Chlamydomonas reinhardtii – Chlamy for short. What follows is a short excerpt: To the casual observer, algae may appear to be a nuisance. But for researchers, photosynthetic microalgae and other microbes have the potential to become sustainable biofactories that can economically produce renewable…
Nathan Price gave a talk titled “Genomics, Big Data, Informatics and the Future of Medicine” at the Personalized Lifestyle Medicine Institute‘s (PLMI) 2015 Thought Leaders Consortium (TLC), held in Chicago, October 24-25. The theme of the 2015 TLC was the Future of Genomics in Healthcare: from Personalized Cancer Therapy to Wellness. Accessing the TLC 2015 videos requires a free subscription on the PLMI’s portal. Please register (for free) on this…
