News

NIH Research Matters features ISB’s MTB paper

NIH Research Matters published an article on our tuberculosis paper. “The incredibly large number of possible drug combinations taken together with the difficulty of growing Mtb in the laboratory make discovery of effective combination therapy extremely challenging,” Dr. Nitin Baliga says. “We hope that our systems-based strategy will accelerate TB drug discovery by helping researchers prioritize combinations that are more likely to be effective.” READ THE ARTICLE

Wilke Cohen Lyme Disease Project Receives $3M from the Steven & Alexandra Cohen Foundation

PRESS RELEASE Total Funding Has Reached $6.1 Million ISB Researchers Have Discovered Potential Biomarkers and Successfully Reproduced the Borrelia Bacteria in the Lab SEATTLE – June 1, 2016 – Institute for Systems Biology (ISB) has received a transformational, multi-year pledge from the Steven & Alexandra Cohen Foundation to support the Wilke Cohen Lyme Disease Project. In addition to an initial $3.1 million in funding from Jeff and Liesl Wilke, Jeff…

ISB Researcher Receives HDSA Fellowship

Congratulations to our colleague Dani Bergey in the Price Lab for receiving a Huntington’s Disease Society of America (HDSA) Donald A. King Summer Research Fellowship. “This is going to be a great step for her as she prepares to apply for graduate school next year,” said Nathan Price.

GiveBIG on May 3 – or schedule your gift now!

ISB is participating in The Seattle Foundation’s sixth annual GiveBIG day on May 3! And, this year, you can schedule your gift in advance. GiveBIG is an annual, community-wide day of giving hosted by The Seattle Foundation that aims to inspire regional philanthropy. Between midnight and midnight (PST) on May 3rd, The Seattle Foundation and its generous sponsors will match a percentage of all contributions to local nonprofits. GiveBIG 2015 raised…

Providence Health & Services and Institute for Systems Biology affiliate to catalyze scientific wellness

Dr. Leroy Hood to serve as chief science officer for Providence FOR IMMEDIATE RELEASE SEATTLE – March 14, 2016 – With the goal of bringing personalized medicine to every patient, Providence Health & Services and the Institute for Systems Biology announced today an affiliation that will transform health care to a proactive mode that is focused on keeping patients well and identifying the earliest opportunities to reverse or even prevent…

“A 100k Wellness Project”, by Nathan Price

A 100k Wellness Project: A Data-Rich Longitudinal Study for the Digital Age was presented by Nathan Price, PhD at the Seattle Science Foundation‘s semi-monthly Spine Conference. Seattle Science Foundation is a non-profit organization dedicated to the international collaboration among physicians, scientists, technologists, engineers and educators. The Foundation’s training facilities and extensive internet connectivity have been designed to foster improvements in health care through professional medical education, training, creative dialogue and…

Learning from microalgae as ‘biofactories’

In a newly published research, former members of the Price lab Saheed Imam and Sascha Schäuble, in collaboration with the Baliga lab, share discoveries from their studies of Chlamydomonas reinhardtii – Chlamy for short. What follows is a short excerpt: To the casual observer, algae may appear to be a nuisance. But for researchers, photosynthetic microalgae and other microbes have the potential to become sustainable biofactories that can economically produce renewable…

Genomics, Big Data, Informatics and the Future of Medicine

Nathan Price gave a talk titled “Genomics, Big Data, Informatics and the Future of Medicine” at the Personalized Lifestyle Medicine Institute‘s (PLMI) 2015 Thought Leaders Consortium (TLC), held in Chicago, October 24-25. The theme of the 2015 TLC was the Future of Genomics in Healthcare: from Personalized Cancer Therapy to Wellness. Accessing the TLC 2015 videos requires a free subscription on the PLMI’s portal. Please register (for free) on this…

Science, tech, design & food converge at reThinkFood conference

ISB Associate Director Dr. Nathan Price participated in the panel discussion “Revolutions in Healthcare: Impacts on the Future of the Food Industry” during the reThinkFood conference at The Culinary Institute of America in Napa Valley. The panelists each gave a short talk about his/her respective interests and then sat down to a discussion. It was an interesting intersection of perspectives from Kevin Slavin (MIT Media Lab), Molly Maloof (Physician Entrepreneur),…

ISB spinout Arivale among ‘Seattle 10’

Geekwire.com announced its latest class of “Seattle 10” – the most innovative startups of the year. Arivale, a scientific wellness company that spun out of ISB’s 100K Wellness Project is one of the featured new companies. “This list showcases 10 of the most promising startup companies in the region— highlighting the very best and brightest.” Read about the Seattle 10…

Dr. Nathan Price at the Vancouver Bioinformatics Users Group 2012: “Integrated modeling of metabolic and regulatory networks”

In this presentation at the the Vancouver Bioinformatics Users Group from 2012, Nathan Price  discusses approaches for the creation of quantitative systems models that can harness the power of genomics, by linking genotype to phenotype. The talk focuses particularly on automated methods for integrating metabolic and regulatory networks, such as Probabilistic Regulation of Metabolism (PROM) (Chandrasekaran and Price, PNAS, 2010). PROM is notable in that it represents the successful integration of a top-down reconstructed,…

WRF gifts $2M to ISB to advance P4 Medicine

PRESS RELEASE from Washington Research Foundation: Sept. 30, 2015, Seattle –– Washington Research Foundation (WRF), which supports groundbreaking technology in the life sciences, physical sciences and information sciences in Washington State, announced today that it will provide the Institute for Systems Biology (ISB) with $2 million in funding to bring increased research power to Seattle, and help place this community at the center of the coming transformation of the health…

Science teaching experience for postdocs

Congratulations to Nyasha Chambwe (Shmulevich Lab) and Vangelis Simeonidis (Price Lab; pictured above) who have been accepted by the UW STEP Program. Formerly called “Future Faculty Fellows Apprenticeship,” the program provides training sessions that introduce effective teaching strategies, and guide participants through the development and teaching of a 10-week course. Rhishi Bargaje (Hood Lab) was a fellow last year.

ISB’s Summer Interns brightest of the bright

Every summer, ISB and ISB’s Center for Systems Biology welcome undergraduate and high school students for internships in our labs. Each student is paired with a mentor and works on research actually taking place in the respective lab. The internships are extremely competitive and we see some of the brightest young minds from across the country. Special thanks and congratulations go to the Price Lab interns, Bijou Basu and Brendan…

Startup Arivale raises $36M series B funding

Arivale, the scientific wellness startup co-founded by ISB President Dr. Lee Hood and Dr. Nathan Price, announced that it raised a $36 million Series B round of funding. Here are some highlights from the coverage so far: Seattle Times Genomeweb FierceBiotech

100K Wellness Project news: Arivale launches

Geekwire.com posted coverage of the launch party of Arivale, a new “scientific wellness” company co-founded by Dr. Nathan Price and Dr. Lee Hood. “I think it’s going to be very big,” said Hood in an interview Monday afternoon at his office. “Arivale is the opening shot in a whole new industry called scientific wellness, and it really stands a chance of being the Google or Microsoft of this whole arena.” Read…

ISB launches 3-Year Wilke Lyme Disease project

Study Utilizes Systems Approaches to Develop Diagnostics and Deeper Understanding of Chronic Lyme The Institute for Systems Biology (ISB) has received $2.13 million in transformational gifts from Jeff and Liesl Wilke; Jeff and MacKenzie Bezos; and the Bay Area Lyme Foundation to tackle chronic Lyme disease, a highly complex and often misdiagnosed disease that can be debilitating for those who do not respond to a standard course of antibiotics. This funding…

NIH-led effort – including ISB – launches Big Data portal for Alzheimer’s drug discovery

The National Institutes of Health announced the launch of a new Alzheimer’s Big Data portal, which includes the first wave of data for use by the research community. This portal is the result of the Accelerating Medicines Partnership (AMP) program, which focuses on facilitating collaboration among government agencies, academia and industry in order to translate research more quickly to therapies. The launch of the AMP Alzeheimers Disease Knowledge Portal is…