Priyanka Baloni, PhD

Senior Research Scientist

Metabolic Modeling

Priyanka Baloni is a postdoctoral fellow in Nathan Price’s lab at the Institute of Systems Biology, Seattle. Her expertise in the field of constraint-based modeling, multi-omics analysis, networks biology, statistical analysis and background in microbiology, biochemistry, molecular biology as well as zoology, has helped her in accomplishing the goals of various projects that she is involved in.

Priyanka obtained her PhD degree from the Indian Institute of Science, Bangalore, India. Her research work mainly focused on identifying the key molecular players in latent tuberculosis infection, one of the forms of TB that goes undetected in the individuals. She obtained her Bachelor of Science degree in Zoology and later, Master of Science degree in Microbiology, and thus transitioned from studying the organisms at macroscopic and microscopic levels. During PhD, she developed her computational skills and got introduced to the field of Systems Biology. Studying host-pathogen interactions interested her to pursue research in this area.

  • Transcriptome analysis
  • Genome-scale metabolic model reconstruction
  • Flux Balance Analysis
  • Network analysis

Selected Publications:

  • Saurabh Mishra, Prashant Shukla, Ashima Bhaskar, Kushi Anand, Priyanka Baloni, Rajiv Kumar Jha, Abhilash Mohan, Raju S Rajmani, Valakunja Nagaraja, Nagasuma Chandra, Amit Singh (2017) Efficacy of β-lactamβ-lactamase inhibitor combination is linked to WhiB4 mediated changes in redox physiology of Mycobacterium tuberculosis eLife 6, e25624
  • Priyanka Baloni, Nagasuma Chandra (2015) Architectural plan of transcriptional regulation in Mycobacterium tuberculosis Trends in Microbiology Volume 23, Issue 3, Pages 123–12
  •  Priyanka Baloni, Jyothi Padiadpu, Anupam Singh, Kuldeepkumar R Gupta, Nagasuma Chandra (2014) Identifying feasible metabolic routes in Mycobacterium smegmatis and possible alterations under diverse nutrient conditions. BMC Microbiology 14 : 279
  • Soma Ghosh*, Priyanka Baloni*, Sumanta Mukherjee, Praveen Anand and Nagasuma Chandra (2013) A multi-level multi-scale approach to study essential genes in Mycobacterium tuberculosis. BMC Systems Biology 7 (1), 132
  • Priyanka Baloni, Soma Ghosh, and Nagasuma Chandra (2015) Systems Approaches to Study Infectious Diseases. Systems and Synthetic Biology. Springer Netherlands, 2015. 151-172.